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Symbol
Name
ID

Chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
MGI:2143558

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased mitochondrial number	Decreased activity of mitochondrial complex II	Decreased activity of mitochondrial complex III	Decreased activity of mitochondrial complex IV	Elevated circulating creatine kinase concentration	Mildly elevated creatine kinase	Increased circulating lactate concentration	Increased intramyocellular lipid droplets	Exercise intolerance
Disease(s) Associated with CHCHD10	Increased mitochondrial number	Decreased activity of mitochondrial complex II	Decreased activity of mitochondrial complex III	Decreased activity of mitochondrial complex IV	Elevated circulating creatine kinase concentration	Mildly elevated creatine kinase	Increased circulating lactate concentration	Increased intramyocellular lipid droplets	Exercise intolerance
isolated mitochondrial myopathy
spinal muscular atrophy, Jokela type

Mouse Phenotypes		homeostasis/metabolism phenotype	impaired exercise endurance	increased circulating creatinine level	increased blood urea nitrogen level	increased circulating phosphate level	increased circulating potassium level
Availability	Mouse Genotype	homeostasis/metabolism phenotype	impaired exercise endurance	increased circulating creatinine level	increased blood urea nitrogen level	increased circulating phosphate level	increased circulating potassium level
	Chchd10^em1(IMPC)H/Chchd10^em1(IMPC)H
	Chchd10^em1(IMPC)Mbp/Chchd10^em1(IMPC)Mbp
	Chchd10^em3Dpn/Chchd10^em3Dpn	*
	Chchd10^em8Lutzy/Chchd10^em8Lutzy
	Chchd10^em8Lutzy/Chchd10⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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