Symbol
Name
ID

Chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
MGI:2143558

Phenotype annotations related to cellular

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased mitochondrial number	Decreased activity of mitochondrial complex II	Decreased activity of mitochondrial complex III	Decreased activity of mitochondrial complex IV
Disease(s) Associated with CHCHD10
isolated mitochondrial myopathy

Mouse Phenotypes

cellular phenotype

decreased myocardial fiber mitochondrial DNA content

cardiac interstitial fibrosis

abnormal cell nucleus morphology

abnormal mitochondrial morphology

abnormal mitochondrial crista morphology

abnormal mitochondrial matrix morphology

increased mitochondrial number

abnormal vacuole morphology

abnormal respiratory electron transport chain

abnormal mitochondrial physiology

Availability

Mouse Genotype

Chchd10^em3Dpn/Chchd10^em3Dpn

Chchd10^em5Lutzy/Chchd10^em5Lutzy

Chchd10^em8Lutzy/Chchd10⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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