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Symbol
Name
ID

Lrrk1
leucine-rich repeat kinase 1
MGI:2142227

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Elevated circulating alkaline phosphatase concentration
Disease(s) Associated with LRRK1	Elevated circulating alkaline phosphatase concentration
osteosclerotic metaphyseal dysplasia

Mouse Phenotypes		homeostasis/metabolism phenotype	increased circulating HDL cholesterol level	increased circulating cholesterol level	increased circulating iron level	increased circulating phosphate level	decreased circulating alkaline phosphatase level	increased circulating aspartate transaminase level	increased circulating creatine kinase level
Availability	Mouse Genotype	homeostasis/metabolism phenotype	increased circulating HDL cholesterol level	increased circulating cholesterol level	increased circulating iron level	increased circulating phosphate level	decreased circulating alkaline phosphatase level	increased circulating aspartate transaminase level	increased circulating creatine kinase level
	Lrrk1^tm1.1Smo/Lrrk1^tm1.1Smo	*
	Lrrk1^{tm1b(KOMP)Wtsi}/Lrrk1^{tm1b(KOMP)Wtsi}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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