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Symbol
Name
ID
Fbxl4
F-box and leucine-rich repeat protein 4
MGI:2140367
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Decreased activity of mitochondrial complex I
Decreased activity of mitochondrial complex III
Decreased activity of mitochondrial complex IV
Mitochondrial respiratory chain defects
Disease(s) Associated with FBXL4
mitochondrial DNA depletion syndrome 13

Mouse Phenotypes
decreased mitochondrial DNA content
decreased mitochondrial number
abnormal oxidative phosphorylation
Availability Mouse Genotype
Fbxl4tm1.2Lrsn/Fbxl4tm1.2Lrsn

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory