|
Symbol Name ID |
Fam20c
FAM20C, golgi associated secretory pathway kinase MGI:2136853 |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal jaw morphology |
Enamel hypomineralization |
Hypocalcification of dental enamel |
Hypomature dental enamel |
Enamel hypoplasia |
| Disease(s) Associated with FAM20C | |||||
| amelogenesis imperfecta |
| Mouse Phenotypes | decreased chondrocyte apoptosis |
dental pulp necrosis |
periodontal ligament necrosis |
impaired osteoblast differentiation |
decreased chondrocyte proliferation |
small cranium |
abnormal jaw morphology |
alveolar process atrophy |
abnormal tooth morphology |
abnormal dental pulp cavity morphology |
conical molar |
small molars |
abnormal periodontal ligament morphology |
abnormal dentin development |
abnormal tooth hard tissue morphology |
abnormal cementum morphology |
abnormal dentin morphology |
absent enamel |
abnormal tooth root morphology |
tooth abscess |
apical tooth abscess |
mandibular hyperostosis |
abnormal maxilla morphology |
abnormal femur morphology |
abnormal limb long bone morphology |
abnormal skeleton morphology |
abnormal long bone diaphysis morphology |
abnormal long bone epiphyseal plate morphology |
abnormal long bone epiphyseal plate proliferative zone |
increased width of hypertrophic chondrocyte zone |
abnormal vertebral column morphology |
abnormal vertebrae morphology |
abnormal bone structure |
decreased bone mineral content |
decreased bone mineral density |
decreased trabecular bone volume |
decreased bone volume |
decreased compact bone thickness |
abnormal osteocyte morphology |
abnormal osteocyte dendritic process morphology |
abnormal osteocyte lacunocanalicular system morphology |
abnormal osteocyte canaliculus morphology |
abnormal osteocyte lacuna morphology |
abnormal trabecular bone morphology |
absent bone trabeculae |
decreased trabecular bone thickness |
osteosclerosis |
abnormal chondrocyte differentiation |
abnormal epiphyseal plate morphology |
decreased bone mineralization |
osteomalacia |
rickets |
delayed endochondral bone ossification |
delayed cranial suture closure |
delayed bone ossification |
fragile skeleton |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fam20ctm1Lex/Fam20ctm1Lex | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fam20ctm1.1Cqi/Fam20ctm1.1Cqi Edil3Tg(Sox2-cre)1Amc/Edil3+ (conditional) |
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| Fam20ctm1.1Cqi/Fam20ctm1.1Cqi Tg(Col1a1-cre)2Bek/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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