Symbol
Name
ID

Alms1
ALMS1, centrosome and basal body associated
MGI:1934606

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased HDL cholesterol concentration	Hypertriglyceridemia	Hyperuricemia	Elevated circulating hepatic transaminase concentration	Hyperglycemia	Insulin-resistant diabetes mellitus	Hyperinsulinemia	Hepatic steatosis
Disease(s) Associated with ALMS1
Alstrom syndrome

Mouse Phenotypes

increased fasting circulating glucose level

hyperglycemia

increased circulating insulin level

increased circulating leptin level

abnormal circulating cholesterol level

increased circulating HDL cholesterol level

increased circulating cholesterol level

increased circulating triglyceride level

increased circulating amylase level

impaired glucose tolerance

insulin resistance

increased urine protein level

albuminuria

crystalluria

Availability

Mouse Genotype

Alms1^bbb/Alms1^bbb

Alms1^foz/Alms1^foz

Alms1^Gt(XH152)Byg/Alms1^Gt(XH152)Byg

Alms1^L2131X/Alms1^L2131X

Alms1^m2Btlr/Alms1^m2Btlr

Alms1^m3Btlr/Alms1^m3Btlr

Alms1^{tm1b(EUCOMM)Hmgu}/Alms1^{tm1b(EUCOMM)Hmgu}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23