Symbol
Name
ID

Smoc1
SPARC related modular calcium binding 1
MGI:1929878

Phenotype annotations related to limbs/digits/tail

Darker colors indicate more annotations

Human Phenotypes

Bowing of the long bones

Tibial bowing

Clinodactyly of the 5th finger

Postaxial hand polydactyly

Camptodactyly of 2nd-5th fingers

Broad thumb

Abnormal thumb morphology

Finger aplasia

Postaxial foot polydactyly

Foot oligodactyly

Sandal gap

Toe syndactyly

2-5 toe syndactyly

2-3 toe cutaneous syndactyly

Finger syndactyly

Fibular hypoplasia

Metatarsal synostosis

Short tibia

Tarsal synostosis

Abnormal metacarpal morphology

4-5 metacarpal synostosis

Abnormality of the lower limb

Pes valgus

Talipes equinovarus

Hip dislocation

Abnormality of the upper limb

Capitate-hamate fusion

Synostosis of carpal bones

Single transverse palmar crease

Bilateral single transverse palmar creases

Elbow dislocation

Disease(s) Associated with SMOC1

microphthalmia with limb anomalies

Mouse Phenotypes

abnormal interdigital cell death

abnormal digit morphology

abnormal pollex morphology

syndactyly

interdigital webbing

clubfoot

pes valgus

abnormal hindlimb morphology

absent fibula

short fibula

bowed tibia

short tibia

fused metatarsal bones

Availability

Mouse Genotype

Smoc1^{tm1a(EUCOMM)Wtsi}/Smoc1^{tm1a(EUCOMM)Wtsi}

Smoc1^{tm1b(EUCOMM)Wtsi}/Smoc1^{tm1b(EUCOMM)Wtsi}

Smoc1^{Tn(sb-lacZ,GFP)IR3.PV384Jtak}/Smoc1^{Tn(sb-lacZ,GFP)IR3.PV384Jtak}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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