Symbol
Name
ID

Tsc1
TSC complex subunit 1
MGI:1929183

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Premature chromatid separation	Lymphedema	Chylothorax	Fever	Abnormal urinary color	Hematuria	Ascites	Cerebral calcification
Disease(s) Associated with TSC1	Premature chromatid separation	Lymphedema	Chylothorax	Fever	Abnormal urinary color	Hematuria	Ascites	Cerebral calcification
lymphangioleiomyomatosis
tuberous sclerosis 1

Mouse Phenotypes

pericardial effusion

abnormal homeostasis

increased circulating follicle stimulating hormone level

increased circulating luteinizing hormone level

decreased circulating ketone body level

decreased circulating triglyceride level

abnormal atrial thrombosis

decreased body temperature

edema

hydrops fetalis

impaired glucose tolerance

insulin resistance

increased incidence of tumors by chemical induction

Availability

Mouse Genotype

Tsc1^tm1.1Djk/Tsc1^tm1.1Djk

Tsc1^tm1Hin/Tsc1⁺

Myl2^tm1(cre)Krc/Myl2⁺
Tsc1^tm1Djk/Tsc1^tm1Djk (conditional)

Tsc1^tm1Djk/Tsc1^tm1Djk (conditional)

Tsc1^tm1Djk/Tsc1^tm1Djk
Tg(Gdf9-icre)5092Coo/? (conditional)

Tsc1^tm1Djk/Tsc1^tm1Djk
Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)

Tg(Tal1-cre/ERT)1Jrg/0
Tsc1^tm1Djk/Tsc1^tm1Djk (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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