Symbol
Name
ID

Mtor
mechanistic target of rapamycin kinase
MGI:1928394

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Elevated circulating creatinine concentration	Type II diabetes mellitus	Insulin resistance	Abnormal urinary electrolyte concentration	Hematuria	Albuminuria
Disease(s) Associated with MTOR	Elevated circulating creatinine concentration	Type II diabetes mellitus	Insulin resistance	Abnormal urinary electrolyte concentration	Hematuria	Albuminuria
autosomal dominant polycystic kidney disease
type 2 diabetes mellitus

Mouse Phenotypes

increased response of heart to induced stress

abnormal autophagy

abnormal translation

decreased blood urea nitrogen level

decreased circulating glucose level

decreased circulating insulin-like growth factor I level

decreased circulating LDL cholesterol level

increased circulating LDL cholesterol level

ascites

pleural effusion

abnormal oxygen consumption

decreased oxygen consumption

increased skeletal muscle glycogen level

abnormal urine homeostasis

Availability

Mouse Genotype

Mtor^tm1.1Clyn/Mtor⁺

Mtor^{tm1a(EUCOMM)Wtsi}/Mtor⁺

Mtor^tm1.1Gcon/Mtor^tm1.1Gcon
A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)

Mtor^tm1.2Koz/Mtor^tm1.2Koz
Tg(ACTA1-cre)79Jme/? (conditional)

Mtor^tm1.1Seq/Mtor^tm1.2Seq
Tg(Nphs2-cre)1Seq/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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