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Symbol
Name
ID

Orai1
ORAI calcium release-activated calcium modulator 1
MGI:1925542

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Hypocalcemia	Elevated circulating creatine kinase concentration	Recurrent fever	Heat intolerance
Disease(s) Associated with ORAI1	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Hypocalcemia	Elevated circulating creatine kinase concentration	Recurrent fever	Heat intolerance
immunodeficiency 9
tubular aggregate myopathy 2

Mouse Phenotypes		decreased platelet calcium level	abnormal platelet activation	abnormal calcium ion homeostasis	decreased leukotriene level
Availability	Mouse Genotype	decreased platelet calcium level	abnormal platelet activation	abnormal calcium ion homeostasis	decreased leukotriene level
	Orai1^Gt(XL922)Byg/Orai1^Gt(XL922)Byg
	Orai1^tm1Fesk/Orai1^tm1Fesk
	Orai1^Gt(XL922)Byg/Orai1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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