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Symbol
Name
ID
Als2
alsin Rho guanine nucleotide exchange factor
MGI:1921268
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Drooling
Urinary incontinence
Depression
Emotional lability
Atypical behavior
Pseudobulbar affect
Agitation
Fatigue
Pain
Disease(s) Associated with ALS2
amyotrophic lateral sclerosis
amyotrophic lateral sclerosis type 2

Mouse Phenotypes
behavior/neurological phenotype
abnormal motor learning
decreased exploration in new environment
increased anxiety-related response
impaired coordination
abnormal physical strength
decreased locomotor activity
Availability Mouse Genotype
Als2tm1Cai/Als2tm1Cai
Als2tm1Deng/Als2tm1Deng
Als2tm1Garo/Als2tm1Garo
Als2tm1Hay/Als2tm1Hay
Als2tm1Jei/Als2tm1Jei *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory