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Symbol
Name
ID
Tmtc4
transmembrane and tetratricopeptide repeat containing 4
MGI:1921050
Phenotype annotations related to hearing/vestibular/ear
Darker colors indicate more annotations

Mouse Phenotypes
cochlear inner hair cell degeneration
cochlear outer hair cell degeneration
cochlear hair cell degeneration
degeneration of organ of Corti supporting cells
organ of Corti degeneration
cochlear degeneration
abnormal auditory brainstem response
abnormal auditory brainstem response waveform shape
increased or absent threshold for auditory brainstem response
increased or absent distortion product otoacoustic emission threshold
absent distortion product otoacoustic emissions
impaired hearing
nonsyndromic hearing loss
sensorineural hearing loss
Availability Mouse Genotype
Tmtc4tm1(KOMP)Vlcg/Tmtc4tm1(KOMP)Vlcg
Tmtc4tm1.1(KOMP)Vlcg/Tmtc4tm1.1(KOMP)Vlcg
Tmtc4em1Dkc/Tmtc4em1Dkc
Myo15atm1.1(cre)Ugds/Myo15a+  (conditional)
Tmtc4em1Dkc/Tmtc4em1Dkc
Tg(Atoh1-cre)1Bfri/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/15/2026
MGI 6.29
The Jackson Laboratory