|
Symbol Name ID |
Spink5
serine peptidase inhibitor, Kazal type 5 MGI:1919682 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Sparse scalp hair |
Sparse eyebrow |
Sparse eyelashes |
Angioedema |
Urticaria |
Eczematoid dermatitis |
Erythroderma |
Recurrent skin infections |
Skin rash |
Abnormal hair morphology |
Trichorrhexis nodosa |
Brittle hair |
Brittle scalp hair |
Fine hair |
Irregular hyperpigmentation |
Dry skin |
Acanthosis nigricans |
Ichthyosis |
Congenital nonbullous ichthyosiform erythroderma |
Parakeratosis |
| Disease(s) Associated with SPINK5 | ||||||||||||||||||||
| Netherton syndrome |
| Mouse Phenotypes | integument phenotype |
impaired skin barrier function |
abnormal hair shaft morphology |
abnormal hair follicle morphology |
abnormal vibrissa follicle morphology |
abnormal vibrissa morphology |
sparse vibrissae |
abnormal epidermal layer morphology |
abnormal epidermis stratum corneum morphology |
abnormal corneocyte envelope morphology |
hyperkeratosis |
parakeratosis |
abnormal epidermis stratum granulosum morphology |
acanthosis |
epidermal desquamation |
blistering |
flaky skin |
reddish skin |
scaly skin |
skin lesions |
decreased skin tensile strength |
|
| Availability | Mouse Genotype | |||||||||||||||||||||
| Spink5m1Btlr/Spink5m1Btlr | ||||||||||||||||||||||
| Spink5tm1Drh/Spink5tm1Drh | ||||||||||||||||||||||
| Spink5tm1Hov/Spink5tm1Hov | ||||||||||||||||||||||
| Spink5Tn(Pgk2-sb10,sb-Tyr)1498Ove/Spink5Tn(Pgk2-sb10,sb-Tyr)1498Ove | * | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools