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Symbol
Name
ID
Wls
wntless WNT ligand secretion mediator
MGI:1915401
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Micrognathia
Microcephaly
Broad distal phalanx of finger
Long fingers
Hypoplasia of the phalanges of the toes
Toe syndactyly
Ectrodactyly
Sacral dimple
Scoliosis
Disease(s) Associated with WLS
Zaki syndrome

Mouse Phenotypes
abnormal neurocranium morphology
abnormal viscerocranium morphology
abnormal tooth morphology
short fibula
short tibia
decreased caudal vertebrae number
abnormal tendon morphology
abnormal skeleton morphology
abnormal ligament morphology
chondrodystrophy
delayed cranial suture closure
delayed bone ossification
Availability Mouse Genotype
Wlsem1Jgg/Wlsem1Jgg
Wlsem2Jgg/Wlsem2Jgg
Wlstm1.1Whsu/Wlstm1.1Whsu
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Wlstm1Xzg/Wlstm1Xzg
Tg(Msx2-cre)5Rem/0  (conditional)
Wlstm1Xzg/Wlstm1Xzg
Tg(Prrx1-cre)1Cjt/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory