Symbol
Name
ID

Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2
MGI:1914762

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hypertriglyceridemia	Elevated circulating hepatic transaminase concentration	Diabetes mellitus	Insulin-resistant diabetes mellitus at puberty	Hyperinsulinemia	Hepatic steatosis	Decreased serum leptin
Disease(s) Associated with AGPAT2
congenital generalized lipodystrophy type 1

Mouse Phenotypes

homeostasis/metabolism phenotype

increased circulating glucose level

hyperglycemia

increased circulating insulin level

decreased circulating leptin level

increased circulating cholesterol level

decreased circulating free fatty acids level

increased circulating triglyceride level

decreased body temperature

abnormal gas homeostasis

increased carbon dioxide production

increased oxygen consumption

decreased respiratory quotient

abnormal glucose homeostasis

improved glucose tolerance

insulin resistance

abnormal lipid homeostasis

abnormal fatty acids level

abnormal phospholipid level

increased liver triglyceride level

Availability

Mouse Genotype

Agpat2^{Gt(OST438470)Lex}/Agpat2^{Gt(OST438470)Lex}

Agpat2^tm1Garg/Agpat2^tm1Garg

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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