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Symbol
Name
ID

Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
MGI:1914175

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased activity of mitochondrial complex II	Abnormal mitochondria in muscle tissue	Increased circulating lactate concentration	Stress/infection-induced lactic acidosis	Elevated lactate:pyruvate ratio	Increased intramyocellular lipid droplets	Elevated urinary catecholamine level	Elevated circulating catecholamine level	Exercise intolerance
Disease(s) Associated with SDHD	Decreased activity of mitochondrial complex II	Abnormal mitochondria in muscle tissue	Increased circulating lactate concentration	Stress/infection-induced lactic acidosis	Elevated lactate:pyruvate ratio	Increased intramyocellular lipid droplets	Elevated urinary catecholamine level	Elevated circulating catecholamine level	Exercise intolerance
mitochondrial complex II deficiency
paraganglioma

Mouse Phenotypes		decreased dopamine level
Availability	Mouse Genotype	decreased dopamine level
	Sdhd^tm1Jlob/Sdhd^tm2Jlob Th^tm1(cre)Te/Th⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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