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Symbol Name ID |
Pnpla2
patatin-like phospholipase domain containing 2 MGI:1914103 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | increased cardiac muscle glycogen level |
increased cardiac muscle triglyceride level |
decreased fatty acid oxidation |
increased susceptibility to diet-induced obesity |
abnormal homeostasis |
impaired adaptive thermogenesis |
abnormal circulating glucose level |
decreased circulating glucose level |
abnormal circulating hormone level |
abnormal circulating insulin level |
decreased circulating insulin level |
increased circulating leptin level |
decreased circulating HDL cholesterol level |
decreased circulating free fatty acids level |
increased circulating free fatty acids level |
decreased circulating triglyceride level |
decreased circulating VLDL triglyceride level |
increased circulating alanine transaminase level |
cardiac edema |
abnormal gas homeostasis |
abnormal oxygen consumption |
decreased oxygen consumption |
abnormal respiratory quotient |
increased respiratory quotient |
abnormal glucose tolerance |
improved glucose tolerance |
increased insulin sensitivity |
abnormal lipid homeostasis |
abnormal lipid level |
increased fatty acids level |
increased liver triglyceride level |
decreased skeletal muscle triglyceride level |
increased skeletal muscle triglyceride level |
increased triglyceride level |
abnormal metabolism |
decreased basal metabolism |
abnormal enzyme/coenzyme activity |
impaired lipolysis |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
| Pnpla2tm1Rze/Pnpla2tm1Rze | |||||||||||||||||||||||||||||||||||||||
| Pnpla2tm1Rze/Pnpla2tm1Rze Tg(Myh6-Pnpla2)94Biat/0 |
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| Tg(Ckm-Pnpla2)164Eek/0 | |||||||||||||||||||||||||||||||||||||||
| Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul Tg(Fabp4-cre)1Rev/0 (conditional) |
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| Pnpla2tm1Eek/Pnpla2tm1Eek Tg(Ckmm-cre)5Khn/0 (conditional) |
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| Pnpla2tm1Eek/Pnpla2tm1Eek Tg(Myog-cre)1Eno/0 (conditional) |
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| Pnpla2tm1Gam/Pnpla2tm1Gam Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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