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Symbol
Name
ID

Nipbl
NIPBL cohesin loading factor
MGI:1913976

Phenotype annotations related to embryo

Darker colors indicate more annotations

Human Phenotypes	Increased nuchal translucency	Prenatal movement abnormality
Disease(s) Associated with NIPBL	Increased nuchal translucency	Prenatal movement abnormality
Cornelia de Lange syndrome

Mouse Phenotypes		decreased cranial neural crest cell proliferation	abnormal pharyngeal arch mesenchyme morphology	decreased embryo size	decreased embryo weight	abnormal placenta junctional zone morphology	abnormal spongiotrophoblast cell morphology	abnormal placenta labyrinth morphology	increased placenta weight	abnormal placenta physiology
Availability	Mouse Genotype	decreased cranial neural crest cell proliferation	abnormal pharyngeal arch mesenchyme morphology	decreased embryo size	decreased embryo weight	abnormal placenta junctional zone morphology	abnormal spongiotrophoblast cell morphology	abnormal placenta labyrinth morphology	increased placenta weight	abnormal placenta physiology
	Nipbl^{Gt(EUCE313f02)1.2Hmgu}/Nipbl⁺
	Nipbl^{Gt(RRS564)Byg}/Nipbl⁺
	Nipbl^tm1.1Hpt/Nipbl^tm1.1Hpt H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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