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Symbol
Name
ID

Crls1
cardiolipin synthase 1
MGI:1913836

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Decreased activity of mitochondrial complex I	Decreased activity of mitochondrial complex III	Decreased activity of mitochondrial complex IV
Disease(s) Associated with CRLS1
combined oxidative phosphorylation deficiency 57

Mouse Phenotypes		decreased fat cell mitochondrial DNA content	decreased adipocyte glucose uptake	disorganized mitochondrial cristae	decreased mitochondrial size	abnormal respiratory electron transport chain
Availability	Mouse Genotype	decreased fat cell mitochondrial DNA content	decreased adipocyte glucose uptake	disorganized mitochondrial cristae	decreased mitochondrial size	abnormal respiratory electron transport chain
	Crls1^tm1Geno/Crls1^tm1Geno Tg(Adipoq-cre)1Evdr/0 (conditional)
	Crls1^tm1Geno/Crls1^tm1Geno Tg(Ucp1-cre/ERT2)426Biat/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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