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Symbol
Name
ID

Tk2
thymidine kinase 2, mitochondrial
MGI:1913266

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Decreased activity of mitochondrial ATP synthase complex	Decreased activity of mitochondrial complex I	Decreased activity of mitochondrial complex III	Decreased activity of mitochondrial complex IV
Disease(s) Associated with TK2
mitochondrial DNA depletion syndrome 2

Mouse Phenotypes		decreased myocardial fiber mitochondrial DNA content	decreased mitochondrial DNA content	decreased muscle fiber mitochondrial DNA content	abnormal mitochondrial crista morphology	abnormal mitochondrial ATP synthesis coupled electron transport
Availability	Mouse Genotype	decreased myocardial fiber mitochondrial DNA content	decreased mitochondrial DNA content	decreased muscle fiber mitochondrial DNA content	abnormal mitochondrial crista morphology
	Tk2^tm1Anka/Tk2^tm1Anka
	Tk2^tm1Mihi/Tk2^tm1Mihi

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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