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Symbol
Name
ID
Txnip
thioredoxin interacting protein
MGI:1889549
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal response of heart to induced stress
abnormal blood homeostasis
increased blood urea nitrogen level
decreased circulating glucose level
hypoglycemia
abnormal circulating insulin level
increased circulating ketone body level
increased circulating lactate level
increased circulating VLDL cholesterol level
increased circulating cholesterol level
increased circulating free fatty acids level
abnormal circulating phospholipid level
increased circulating triglyceride level
increased circulating calcium level
increased circulating phosphate level
increased circulating potassium level
decreased circulating sodium level
decreased circulating antithrombin level
decreased circulating alkaline phosphatase level
increased partial thromboplastin time
increased prothrombin time
increased bleeding time
abnormal glucose homeostasis
abnormal gluconeogenesis
improved glucose tolerance
increased insulin sensitivity
abnormal lipid homeostasis
increased fatty acids level
hematuria
decreased physiological sensitivity to xenobiotic
Availability Mouse Genotype
TxnipHyplip1/TxnipHyplip1
Txniptm1.1Rlee/Txniptm1.1Rlee *
Txniptm1.1Road/Txniptm1.1Road
Txniptm1b(EUCOMM)Hmgu/Txniptm1b(EUCOMM)Hmgu
Txniptm1Jjy/Txniptm1Jjy
Txniptm1Rlee/Txniptm1Rlee
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+  (conditional)
Txniptm1Road/Txniptm1Road
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
*
Txniptm1Road/Txniptm1Road
Tg(Ckmm-cre)5Khn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory