Symbol
Name
ID

Lmx1a
LIM homeobox transcription factor 1 alpha
MGI:1888519

Phenotype annotations related to hearing/vestibular/ear

Darker colors indicate more annotations

Human Phenotypes	High-frequency hearing impairment
Disease(s) Associated with LMX1A	High-frequency hearing impairment
autosomal dominant nonsyndromic deafness 7

Mouse Phenotypes

abnormal bony labyrinth

abnormal ear development

abnormal otic vesicle development

abnormal inner ear morphology

abnormal cochlea morphology

abnormal cochlear inner hair cell morphology

short scala media

abnormal semicircular canal morphology

absent semicircular canals

abnormal inner ear vestibule morphology

abnormal utricle morphology

absent utricle

abnormal vestibular saccule morphology

absent vestibular saccule

abnormal membranous labyrinth morphology

abnormal cochlear labyrinth morphology

abnormal vestibular labyrinth morphology

dilated endolymphatic duct

dilated endolymphatic sac

absent otoliths

inner ear hypoplasia

increased or absent threshold for auditory brainstem response

impaired hearing

deafness

syndromic hearing loss

Availability

Mouse Genotype

Lmx1a^bsd/Lmx1a^bsd

Lmx1a^dr-2J/Lmx1a^dr-2J

Lmx1a^dr-6J/Lmx1a^dr-6J

Lmx1a^dr-10J/Lmx1a^dr-10J

Lmx1a^dr-J/Lmx1a^dr-J

Lmx1a^dr-sst/Lmx1a^dr-sst

Lmx1a^dr/Lmx1a^dr

Lmx1a^mtl/Lmx1a^mtl

Lmx1a^bsd/Lmx1a^mtl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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