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Symbol
Name
ID
Wdr45
WD repeat domain 45
MGI:1859606
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Aggressive behavior
Disease(s) Associated with WDR45
neurodegeneration with brain iron accumulation 5

Mouse Phenotypes
behavior/neurological phenotype
impaired contextual conditioning behavior
impaired spatial learning
abnormal spatial working memory
abnormal startle reflex
limb grasping
tremors
impaired coordination
increased locomotor activity
hyperactivity
abnormal social recognition
Availability Mouse Genotype
Wdr45em1Wrst/Wdr45em1Wrst
Wdr45em1Wrst/Wdr45+
Wdr45em1(IMPC)J/Y
Wdr45em1Wrst/Y
Wdr45tm1Beij/Y
Tg(Nes-cre)1Kln/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory