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Symbol
Name
ID

Icos
inducible T cell co-stimulator
MGI:1858745

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Secretory IgA deficiency	Impaired T cell function
Disease(s) Associated with ICOS	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Secretory IgA deficiency	Impaired T cell function
common variable immunodeficiency 1
immunoglobulin alpha deficiency

Mouse Phenotypes		decreased circulating interferon-gamma level	decreased circulating interleukin-4 level	abnormal interferon level	abnormal interleukin level
Availability	Mouse Genotype	decreased circulating interferon-gamma level	decreased circulating interleukin-4 level	abnormal interferon level	abnormal interleukin level
	Icos^tm1Flv/Icos^tm1Flv
	Icos^tm1Shr/Icos^tm1Shr
	Icos^tm1Tkan/Icos^tm1Tkan

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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