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Symbol
Name
ID
Chek2
checkpoint kinase 2
MGI:1355321
Phenotype annotations related to neoplasm
Darker colors indicate more annotations
Human Phenotypes
Breast carcinoma
Hereditary nonpolyposis colorectal carcinoma
Neoplasm of the stomach
Stomach cancer
Retinoblastoma
Prostate cancer
Uterine leiomyosarcoma
Renal cell carcinoma
Bladder neoplasm
Transitional cell carcinoma of the bladder
Osteosarcoma
Glioma
Meningioma
Sarcoma
Disease(s) Associated with CHEK2
breast cancer
colorectal cancer
Li-Fraumeni syndrome 2
osteosarcoma
prostate cancer
urinary bladder cancer

Mouse Phenotypes
increased incidence of tumors by chemical induction
Availability Mouse Genotype
Chek2tm1Mak/Chek2tm1Mak

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory