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Symbol
Name
ID

Ercc4
excision repair cross-complementing rodent repair deficiency, complementation group 4
MGI:1354163

Phenotype annotations related to cellular

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Chromosome breakage	Defective DNA repair after ultraviolet radiation damage	Deficient excision of UV-induced pyrimidine dimers in DNA
Disease(s) Associated with ERCC4	Chromosome breakage	Defective DNA repair after ultraviolet radiation damage	Deficient excision of UV-induced pyrimidine dimers in DNA
Fanconi anemia complementation group Q
xeroderma pigmentosum group F
XFE progeroid syndrome

Mouse Phenotypes		cellular phenotype	increased hepatocyte karyomegaly	increased cellular sensitivity to alkylating agents	increased cellular sensitivity to ultraviolet irradiation	abnormal DNA repair
Availability	Mouse Genotype
	Ercc4^tm1Fwa/Ercc4^tm1Fwa	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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