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Symbol
Name
ID

Abcc8
ATP-binding cassette, sub-family C member 8
MGI:1352629

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Reduced C-peptide level	Hyperglycemia	Hypoglycemia	Hypoglycemic seizures	Diabetes mellitus	Type I diabetes mellitus	Type II diabetes mellitus	Hyperinsulinemic hypoglycemia	Insulin resistance
Disease(s) Associated with ABCC8	Reduced C-peptide level	Hyperglycemia	Hypoglycemia	Hypoglycemic seizures	Diabetes mellitus	Type I diabetes mellitus	Type II diabetes mellitus	Hyperinsulinemic hypoglycemia	Insulin resistance
familial hyperinsulinemic hypoglycemia 1
leucine-sensitive hypoglycemia of infancy
permanent neonatal diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes		homeostasis/metabolism phenotype	abnormal insulin secretion	decreased insulin secretion	increased insulin secretion	decreased circulating glucose level	hypoglycemia	increased circulating glucose level	impaired glucose tolerance
Availability	Mouse Genotype	homeostasis/metabolism phenotype	abnormal insulin secretion	decreased insulin secretion	increased insulin secretion	decreased circulating glucose level	hypoglycemia	increased circulating glucose level	impaired glucose tolerance
	Abcc8^em1(IMPC)J/Abcc8^em1(IMPC)J
	Abcc8^tm1.1Fmas/Abcc8^tm1.1Fmas	*
	Abcc8^tm1.1Mgn/Abcc8^tm1.1Mgn
	Abcc8^tm1Jbry/Abcc8^tm1Jbry

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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