|
Symbol Name ID |
Nr1h3
nuclear receptor subfamily 1, group H, member 3 MGI:1352462 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased resting energy expenditure |
| Disease(s) Associated with NR1H3 | |
| obesity |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal cellular cholesterol metabolism |
decreased circulating testosterone level |
increased circulating estradiol level |
decreased circulating luteinizing hormone level |
increased circulating LDL cholesterol level |
increased circulating cholesterol level |
increased circulating alanine transaminase level |
increased circulating aspartate transaminase level |
increased erythrocyte sedimentation rate |
abnormal lipid homeostasis |
abnormal bile salt homeostasis |
abnormal cholesterol homeostasis |
increased liver cholesterol level |
increased liver triglyceride level |
decreased physiological sensitivity to xenobiotic |
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| Availability | Mouse Genotype | ||||||||||||||||
| Nr1h3tm1.1(KOMP)Vlcg/Nr1h3tm1.1(KOMP)Vlcg | |||||||||||||||||
| Nr1h3tm1.1Gstr/Nr1h3tm1.1Gstr | |||||||||||||||||
| Nr1h3tm1.1Nph/Nr1h3tm1.1Nph | * | ||||||||||||||||
| Nr1h3tm1Dgen/Nr1h3tm1Dgen | |||||||||||||||||
| Nr1h3tm1Djm/Nr1h3tm1Djm | * | ||||||||||||||||
| Tg(Fabp1-Nr1h3)#Wexi/? | |||||||||||||||||
| Nr1h3tm1.1Djm/Nr1h3tm1.1Djm Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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