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Symbol
Name
ID

Grm8
glutamate receptor, metabotropic 8
MGI:1351345

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes	Hyperactivity	Attention deficit hyperactivity disorder	Lack of spontaneous play	Reduced ability to form peer relationships	Autism	Schizophrenia	Motor stereotypy	Addictive alcohol use	Inflexible adherence to routines	Restrictive behavior
Disease(s) Associated with GRM8	Hyperactivity	Attention deficit hyperactivity disorder	Lack of spontaneous play	Reduced ability to form peer relationships	Autism	Schizophrenia	Motor stereotypy	Addictive alcohol use	Inflexible adherence to routines	Restrictive behavior
alcohol dependence
attention deficit hyperactivity disorder
autistic disorder
schizophrenia

Mouse Phenotypes		decreased exploration in new environment	increased anxiety-related response	impaired swimming	abnormal locomotor behavior
Availability	Mouse Genotype	decreased exploration in new environment	increased anxiety-related response	impaired swimming	abnormal locomotor behavior
	Grm8^tm1Dgen/Grm8^tm1Dgen
	Grm8^tm1Duv/Grm8^tm1Duv

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/15/2026 MGI 6.29