Symbol
Name
ID

Ofd1
OFD1, centriole and centriolar satellite protein
MGI:1350328

Phenotype annotations related to limbs/digits/tail

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Clinodactyly of the 5th finger

Postaxial hand polydactyly

Broad thumb

Hand polydactyly

Preaxial hand polydactyly

Short finger

Deviation of finger

Radial deviation of finger

Short toe

Short 2nd toe

Foot polydactyly

Clinodactyly

Polydactyly

Brachydactyly

Syndactyly

Finger syndactyly

Tarsal synostosis

Disease(s) Associated with OFD1

orofaciodigital syndrome I

Simpson-Golabi-Behmel syndrome type 2

Mouse Phenotypes

limbs/digits/tail phenotype

abnormal limb mesenchyme morphology

polydactyly

preaxial polydactyly

syndactyly

abnormal humerus morphology

short humerus

short radius

short ulna

short femur

short fibula

short tibia

abnormal limb development

short limbs

Availability

Mouse Genotype

Ofd1^tm1Bfra/Ofd1^tm1Bfra

Ofd1^tm2.1Bfra/Ofd1⁺
Tg(CAG-cre)1Nagy/0 (conditional)

Ofd1^tm2.1Bfra/Ofd1⁺
Tg(Prrx1-cre)1Cjt/0 (conditional)

Ofd1^tm2.1Bfra/Y
Tg(Prrx1-cre)1Cjt/0 (conditional)

Ofd1^tm2.1Bfra/Y
Tg(Msx2-cre)5Rem/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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