|
Symbol Name ID |
Foxc2
forkhead box C2 MGI:1347481 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Micrognathia |
Cleft upper lip |
Cleft palate |
Conjunctivitis |
Distichiasis |
Ectropion |
| Disease(s) Associated with FOXC2 | ||||||
| lymphedema-distichiasis syndrome |
| Mouse Phenotypes | craniofacial phenotype |
abnormal fourth pharyngeal arch artery morphology |
abnormal third pharyngeal arch artery morphology |
abnormal craniofacial bone morphology |
small basioccipital bone |
abnormal basisphenoid bone morphology |
abnormal Meckel's cartilage morphology |
small Meckel's cartilage |
small interparietal bone |
small exoccipital bone |
abnormal supraoccipital bone morphology |
absent supraoccipital bone |
abnormal sphenoid bone morphology |
abnormal alisphenoid bone morphology |
abnormal presphenoid bone morphology |
absent presphenoid bone |
abnormal pterygoid process morphology |
small pterygoid bone |
small temporal bone squamous part |
abnormal orbit morphology |
small mandible |
abnormal palatine bone horizontal plate morphology |
absent palatine bone horizontal plate |
absent palatine bone |
abnormal middle ear ossicle morphology |
absent incus |
abnormal malleus morphology |
abnormal gonial bone morphology |
gonial bone hypoplasia |
malleus hypoplasia |
absent stapes |
absent soft palate |
cleft secondary palate |
cleft palate |
periorbital edema |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
| Foxc2tm1Blh/Foxc2tm1Blh | ||||||||||||||||||||||||||||||||||||
| Foxc2tm1Miu/Foxc2tm1Miu | ||||||||||||||||||||||||||||||||||||
| Foxc2tm1Miu/Foxc2+ | ||||||||||||||||||||||||||||||||||||
| Foxc2tm1.1Miu/Foxc2tm1.1Miu Nkx2-5tm1(cre)Rjs/Nkx2-5+ (conditional) |
* | |||||||||||||||||||||||||||||||||||
| Foxc2tm1.1Miu/Foxc2tm1.1Miu Tg(Tek-cre)1Ywa/0 (conditional) |
* | |||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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