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Symbol
Name
ID
Grem1
gremlin 1, DAN family BMP antagonist
MGI:1344337
Phenotype annotations related to skeleton
Darker colors indicate more annotations

Mouse Phenotypes
enhanced osteoblast differentiation
polyphalangy
fused radius and ulna
bowed femur
abnormal fibula morphology
absent fibula
short fibula
abnormal tibia morphology
bowed tibia
abnormal limb long bone morphology
fused metacarpal bones
abnormal long bone morphology
increased trabecular bone volume
increased trabecular bone thickness
increased bone mineralization
increased bone ossification
Availability Mouse Genotype
Grem1ld/Grem1ld
Grem1tm1Azun/Grem1tm1Azun
Gt(ROSA)26Sortm1(Grem1)Svok/Gt(ROSA)26Sortm1(Grem1)Svok
Tg(Hoxb6-cre/ERT)1Smac/0  (conditional)
Grem1tm1Ecan/Grem1tm1Rmh
Tg(BGLAP-cre)1Clem/0  (conditional)
Gt(ROSA)26Sortm1(Grem1)Svok/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/0  (conditional)
Gt(ROSA)26Sortm1(Grem1)Svok/Gt(ROSA)26Sor+
Tg(Hoxb6-cre/ERT)1Smac/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory