|
Symbol Name ID |
Msh6
mutS homolog 6 MGI:1343961 |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukemia |
Hematological neoplasm |
Lymphoma |
Non-Hodgkin lymphoma |
T-cell lymphoma |
Adenoma sebaceum |
Salivary gland neoplasm |
Breast carcinoma |
Neoplasm of the rectum |
Adenocarcinoma of the colon |
Hereditary nonpolyposis colorectal carcinoma |
Adenomatous colonic polyposis |
Colon cancer |
Intestinal polyposis |
Neoplasm of the stomach |
Neoplasm of the liver |
Hepatocellular carcinoma |
Neoplasm of the pancreas |
Pancreatic adenocarcinoma |
Adenocarcinoma of the small intestine |
Pituitary adenoma |
Neoplasm of the thyroid gland |
Ovarian neoplasm |
Endometrial carcinoma |
Renal neoplasm |
Malignant genitourinary tract tumor |
Urinary tract neoplasm |
Neoplasm of the skin |
Basal cell carcinoma |
Plexiform neurofibroma |
Rhabdomyosarcoma |
Neoplasm of the skeletal system |
Astrocytoma |
Pleomorphic xanthoastrocytoma |
Ependymoma |
Glioblastoma multiforme |
Oligodendroglioma |
Benign neoplasm of the central nervous system |
Medulloblastoma |
Neuroblastoma |
Laryngeal carcinoma |
| Disease(s) Associated with MSH6 | |||||||||||||||||||||||||||||||||||||||||
| endometrial cancer | |||||||||||||||||||||||||||||||||||||||||
| hereditary nonpolyposis colorectal cancer type 5 | |||||||||||||||||||||||||||||||||||||||||
| Lynch syndrome | |||||||||||||||||||||||||||||||||||||||||
| mismatch repair cancer syndrome |
| Mouse Phenotypes | increased gastrointestinal tumor incidence |
increased intestinal adenoma incidence |
increased skin tumor incidence |
increased basal cell carcinoma incidence |
increased lymphoma incidence |
increased hemolymphoid system tumor incidence |
increased uterus tumor incidence |
increased tumor incidence |
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| Availability | Mouse Genotype | ||||||||
| Msh6tm1Htr/Msh6tm1Htr | |||||||||
| Msh6tm1Rak/Msh6tm1Rak | |||||||||
| Msh6tm1Wed/Msh6tm1Wed | |||||||||
| Msh6tm1Wed/Msh6+ | |||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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