About Help FAQ

Symbol
Name
ID

Ndufs4
NADH:ubiquinone oxidoreductase core subunit S4
MGI:1343135

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Decreased activity of mitochondrial respiratory chain	Decreased activity of mitochondrial complex I	Decreased activity of mitochondrial complex II	Decreased activity of mitochondrial complex III	Decreased activity of mitochondrial complex IV	Decreased activity of the pyruvate dehydrogenase complex
Disease(s) Associated with NDUFS4
Leigh disease

Mouse Phenotypes		abnormal mitochondrial crista morphology	abnormal respiratory electron transport chain	abnormal mitochondrial ATP synthesis coupled electron transport	oxidative stress
Availability	Mouse Genotype	abnormal mitochondrial crista morphology	abnormal respiratory electron transport chain		oxidative stress
	Ndufs4^tm1.1Rpa/Ndufs4^tm1.1Rpa
	Ndufs4^tm1Capt/Ndufs4⁺
	Ndufs4^tm1Rpa/Ndufs4^tm1Rpa Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23