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Symbol Name ID |
Ndufs4
NADH:ubiquinone oxidoreductase core subunit S4 MGI:1343135 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Feeding difficulties |
Emotional lability |
| Disease(s) Associated with NDUFS4 | ||
| Leigh disease |
| Mouse Phenotypes | behavior/neurological phenotype |
lethargy |
abnormal emotion/affect behavior |
decreased aggression |
decreased grooming behavior |
abnormal motor capabilities/coordination/movement |
impaired righting response |
hyporesponsive to tactile stimuli |
decreased startle reflex |
hyperekplexia |
limb grasping |
tremors |
abnormal motor coordination/balance |
ataxia |
impaired balance |
impaired coordination |
impaired swimming |
abnormal posture |
hunched posture |
trunk curl |
head tilt |
straub tail |
tail dragging |
abnormal gait |
decreased locomotor activity |
positive geotaxis |
retropulsion |
circling |
abnormal sensory capabilities/reflexes/nociception |
abnormal nest building behavior |
decreased vocalization |
seizures |
environmentally induced seizures |
tonic-clonic seizures |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||
| Ndufs4fky/Ndufs4fky | |||||||||||||||||||||||||||||||||||
| Ndufs4tm1.1Rpa/Ndufs4tm1.1Rpa | |||||||||||||||||||||||||||||||||||
| Ndufs4tm1Rpa/Ndufs4tm1Rpa Tg(Pcp2-cre)3555Jdhu/0 (conditional) |
* | ||||||||||||||||||||||||||||||||||
| Ndufs4tm1Rpa/Ndufs4tm1Rpa Tg(Nes-cre)1Kln/0 (conditional) |
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| Ndufs4tm1Rpa/Ndufs4tm1Rpa (conditional) | |||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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