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Symbol Name ID |
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha MGI:1342774 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased waist to hip ratio |
Cachexia |
| Disease(s) Associated with PPARGC1A | ||
| amyotrophic lateral sclerosis | ||
| type 2 diabetes mellitus |
| Mouse Phenotypes | decreased body fat mass |
increased heart weight |
cardiac hypertrophy |
growth/size/body region phenotype |
decreased lean body mass |
decreased body weight |
cachexia |
decreased body length |
abnormal body weight |
decreased susceptibility to diet-induced obesity |
increased susceptibility to weight gain |
increased kidney weight |
increased lung weight |
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| Availability | Mouse Genotype | |||||||||||||
| Ppargc1atm1Aztc/Ppargc1atm1Aztc | ||||||||||||||
| Ppargc1atm1Brsp/Ppargc1atm1Brsp | ||||||||||||||
| Ppargc1atm1Dpk/Ppargc1atm1Dpk | ||||||||||||||
| Ppargc1atm1Aztc/Ppargc1a+ | ||||||||||||||
| Tg(Myh6-rtTA)8585Jam/0 Tg(tetO-Ppargc1a)1Dpk/0 |
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| Tg(Myog-Ppargc1a_i4)#Brsp/0 | ||||||||||||||
| Ppargc1atm1.1Javi/Ppargc1atm1.1Javi Tg(Fabp4-cre)1Rev/0 (conditional) |
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| Ppargc1atm2.1Brsp/Ppargc1atm2.1Brsp Tg(Myog-cre)1Eno/0 (conditional) |
* | |||||||||||||
| Ppargc1atm1Brsp/Ppargc1atm2Brsp Tg(Myog-cre)1Eno/0 (conditional) |
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| Ppargc1atm2Brsp/Ppargc1a+ Tg(Myog-cre)1Eno/0 (conditional) |
* | |||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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