|
Symbol Name ID |
Stk11
serine/threonine kinase 11 MGI:1341870 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Neoplasm of the nose |
Breast carcinoma |
Esophageal neoplasm |
Neoplasm of the rectum |
Neoplasm of the colon |
Colon cancer |
Hamartomatous polyposis |
Multiple gastric polyps |
Stomach cancer |
Biliary tract neoplasm |
Neoplasm of the liver |
Neoplasm of the pancreas |
Pancreatic adenocarcinoma |
Gastrointestinal carcinoma |
Neoplasm of the small intestine |
Precocious puberty with Sertoli cell tumor |
Ovarian carcinoma |
Cervix cancer |
Uterine neoplasm |
Renal cell carcinoma |
Neoplasm of the lung |
Neoplasm |
Melanoma |
| Disease(s) Associated with STK11 | |||||||||||||||||||||||
| pancreatic cancer | |||||||||||||||||||||||
| Peutz-Jeghers syndrome |
| Mouse Phenotypes | neoplasm |
increased gastrointestinal tumor incidence |
increased intestinal adenoma incidence |
increased incidence of tumors by chemical induction |
increased hepatocellular carcinoma incidence |
increased liver adenoma incidence |
increased metastatic potential |
increased adenoma incidence |
increased hamartoma incidence |
increased hemangioma incidence |
increased endometrial carcinoma incidence |
increased squamous cell carcinoma incidence |
decreased tumor incidence |
increased tumor incidence |
|
| Availability | Mouse Genotype | ||||||||||||||
| Stk11tm1.1Jish/Stk11+ | |||||||||||||||
| Stk11tm1.1Mlfr/Stk11+ | |||||||||||||||
| Stk11tm1.2Rdp/Stk11+ | |||||||||||||||
| Stk11tm1Mmt/Stk11+ | |||||||||||||||
| Stk11tm1Tpm/Stk11+ | |||||||||||||||
| Stk11tm1.1Rdp/Stk11tm1.1Rdp (conditional) | * | ||||||||||||||
| Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(KRT14-cre)1Ipc/0 (conditional) |
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| Stk11tm1.1Rdp/Stk11tm1.1Rdp Taglntm1(cre/ERT2)Feil/Tagln+ (conditional) |
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| Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(Sprr2f-cre)1Dcas/0 (conditional) |
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| Stk11tm1.1Rdp/Stk11tm1.1Rdp Isl1tm1(cre)Tmj/Isl1+ (conditional) |
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| Amhr2tm3(cre)Bhr/Amhr2+ Stk11tm1Rdp/Stk11tm1Rdp (conditional) |
* | ||||||||||||||
| Stk11tm1.1Rdp/Stk11+ Taglntm1(cre/ERT2)Feil/Tagln+ (conditional) |
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| Stk11tm1.1Rdp/Stk11tm1.2Rdp (conditional) | * | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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