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Symbol
Name
ID
Trp73
transformation related protein 73
MGI:1336991
Phenotype annotations related to neoplasm
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Breast carcinoma
Hereditary nonpolyposis colorectal carcinoma
Neoplasm of the stomach
Cervix cancer
Uterine leiomyosarcoma
Nephroblastoma
Renal cell carcinoma
Transitional cell carcinoma of the bladder
Neoplasm of the lung
Alveolar cell carcinoma
Non-small cell lung carcinoma
Lung adenocarcinoma
Neoplasm
Disease(s) Associated with TP73
breast cancer
cervical cancer
colorectal cancer
lung cancer
lung small cell carcinoma
nephroblastoma
renal cell carcinoma

Mouse Phenotypes
neoplasm
increased T cell derived lymphoma incidence
increased incidence of tumors by chemical induction
increased lung adenoma incidence
increased lymphoma incidence
increased malignant tumor incidence
increased carcinoma incidence
increased lung adenocarcinoma incidence
increased hemangiosarcoma incidence
increased tumor incidence
Availability Mouse Genotype
Trp73tm1Fmc/Trp73tm1Fmc *
Trp73tm1Mak/Trp73tm1Mak
Trp73tm1Fmc/Trp73+
Trp73tm1Mak/Trp73+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory