|
Symbol Name ID |
Bub1b
BUB1B, mitotic checkpoint serine/threonine kinase MGI:1333889 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukemia |
Hereditary nonpolyposis colorectal carcinoma |
Neoplasm of the stomach |
Uterine leiomyosarcoma |
Nephroblastoma |
Renal cell carcinoma |
Transitional cell carcinoma of the bladder |
Embryonal rhabdomyosarcoma |
| Disease(s) Associated with BUB1B | ||||||||
| colorectal cancer | ||||||||
| mosaic variegated aneuploidy syndrome 1 |
| Mouse Phenotypes | neoplasm |
increased colon adenoma incidence |
increased intestinal adenocarcinoma incidence |
increased rectum adenocarcinoma incidence |
increased incidence of tumors by chemical induction |
increased hepatocellular carcinoma incidence |
increased tumor growth/size |
increased leukemia incidence |
increased lymphoma incidence |
increased B cell derived lymphoma incidence |
increased adenocarcinoma incidence |
increased lung adenocarcinoma incidence |
increased sarcoma incidence |
increased fibrosarcoma incidence |
increased hemangiosarcoma incidence |
increased incidence of induced tumors |
decreased tumor latency |
|
| Availability | Mouse Genotype | |||||||||||||||||
| Bub1bGt(neo-btk)1Dai/Bub1b+ | ||||||||||||||||||
| Bub1btm1.1Hsl/Bub1b+ | ||||||||||||||||||
| Bub1btm1.1Jvd/Bub1b+ | * | |||||||||||||||||
| Bub1btm1Jvd/Bub1btm3.1Jvd | * | |||||||||||||||||
| Bub1btm2.1Jvd/Bub1b+ | * | |||||||||||||||||
| Bub1btm3.1Jvd/Bub1b+ | * | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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