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Symbol Name ID |
Bub1b
BUB1B, mitotic checkpoint serine/threonine kinase MGI:1333889 |
| Darker colors indicate more annotations |
| Human Phenotypes | Premature chromatid separation |
| Disease(s) Associated with BUB1B | |
| mosaic variegated aneuploidy syndrome 1 |
| Mouse Phenotypes | oligozoospermia |
abnormal cell nucleus morphology |
abnormal chromosome number |
aneuploidy |
abnormal cell physiology |
abnormal cell cycle checkpoint function |
abnormal mitotic spindle assembly checkpoint |
abnormal mitosis |
abnormal mitotic spindle morphology |
increased embryonic tissue cell apoptosis |
increased apoptosis |
abnormal megakaryocyte differentiation |
increased B cell proliferation |
abnormal cellular replicative senescence |
early cellular replicative senescence |
chromosome breakage |
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| Availability | Mouse Genotype | ||||||||||||||||
| Bub1bGt(neo-btk)1Dai/Bub1bGt(neo-btk)1Dai | |||||||||||||||||
| Bub1btm1.1Hsl/Bub1btm1.1Hsl | |||||||||||||||||
| Bub1btm1Jvd/Bub1btm1Jvd | |||||||||||||||||
| Bub1bGt(neo-btk)1Dai/Bub1b+ | |||||||||||||||||
| Bub1btm1.1Hsl/Bub1b+ | |||||||||||||||||
| Bub1btm1.1Hsl/Bub1b+ Tg(HIST1H2BB/EGFP)1Pa/0 |
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| Bub1btm1.1Jvd/Bub1b+ | |||||||||||||||||
| Bub1btm1Jvd/Bub1b+ | |||||||||||||||||
| Bub1btm1Jvd/Bub1btm2.1Jvd | |||||||||||||||||
| Bub1btm1Jvd/Bub1btm3.1Jvd | |||||||||||||||||
| Bub1btm2.1Jvd/Bub1b+ | |||||||||||||||||
| Bub1btm3.1Jvd/Bub1b+ | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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