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Symbol
Name
ID
Soat2
sterol O-acyltransferase 2
MGI:1332226
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased LDL cholesterol concentration
Hypercholesterolemia
Hypertriglyceridemia
Glucose intolerance
Diabetes mellitus
Type II diabetes mellitus
Impaired glucose tolerance
Disease(s) Associated with SOAT2
coronary artery disease

Mouse Phenotypes
decreased intestinal cholesterol absorption
increased circulating HDL cholesterol level
decreased circulating LDL cholesterol level
decreased circulating VLDL cholesterol level
decreased circulating cholesterol level
increased circulating triglyceride level
abnormal cholesterol homeostasis
decreased liver cholesterol level
decreased cholesterol level
increased cholesterol level
decreased liver triglyceride level
Availability Mouse Genotype
Soat2tm1Far/Soat2tm1Far
Soat2tm1.1Llr/Soat2tm1.1Llr
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Soat2tm1.1Llr/Soat2tm1.1Llr
Tg(Vil1-cre)997Gum/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory