|
Symbol Name ID |
Trp63
transformation related protein 63 MGI:1330810 |
| Darker colors indicate more annotations |
| Human Phenotypes | Micrognathia |
Hypoplasia of the maxilla |
Malar flattening |
Microcephaly |
Abnormal dental enamel morphology |
Enamel hypoplasia |
Clinodactyly of the 5th finger |
Aplasia/Hypoplasia of the phalanges of the hand |
Triphalangeal thumb |
Aplasia/Hypoplasia of the phalanges of the toes |
Toe syndactyly |
2-3 toe syndactyly |
2-3 toe cutaneous syndactyly |
Syndactyly |
Finger syndactyly |
Aplasia/Hypoplasia of metatarsal bones |
Aplasia/Hypoplasia involving the metacarpal bones |
Ectrodactyly |
Split foot |
Split hand |
Abnormal skeletal morphology |
Hypoplastic sacrum |
Abnormal joint morphology |
| Disease(s) Associated with TP63 | |||||||||||||||||||||||
| ADULT syndrome | |||||||||||||||||||||||
| ankyloblepharon-ectodermal defects-cleft lip/palate syndrome | |||||||||||||||||||||||
| bladder exstrophy-epispadias-cloacal exstrophy complex | |||||||||||||||||||||||
| ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3 | |||||||||||||||||||||||
| Rapp-Hodgkin syndrome | |||||||||||||||||||||||
| split hand-foot malformation 4 |
| Mouse Phenotypes | abnormal tooth development |
absent tooth placode |
absent teeth |
supernumerary teeth |
abnormal tooth root morphology |
small mandible |
small maxilla |
absent carpal bone |
abnormal phalanx morphology |
abnormal humerus morphology |
absent radius |
absent ulna |
abnormal limb bone morphology |
abnormal pelvic girdle bone morphology |
absent pubic symphysis |
intervertebral disk degeneration |
kyphosis |
lordokyphosis |
|
| Availability | Mouse Genotype | ||||||||||||||||||
| Trp63tm1.1Elrf/Trp63tm1.1Elrf | |||||||||||||||||||
| Trp63tm1Brd/Trp63tm1Brd | |||||||||||||||||||
| Trp63tm1Fmc/Trp63tm1Fmc | |||||||||||||||||||
| Trp63tm2Brd/Trp63tm2Brd | |||||||||||||||||||
| Trp63tm1Aam/Trp63+ | |||||||||||||||||||
| Trp63tm1Fmc/Trp63+ | |||||||||||||||||||
| Trp63tm3Aam/Trp63+ | |||||||||||||||||||
| Tg(KRT5-cre/PGR)1Der/0 Trp63tm2Brd/Trp63tm3.1Brd (conditional) |
|||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|
|
||
Analysis Tools