About Help FAQ

Symbol
Name
ID

Matn3
matrilin 3
MGI:1328350

Phenotype annotations related to skeleton

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Genu valgum

Genu varum

Osteoarthritis of the small joints of the hand

Hypoplasia of the capital femoral epiphysis

Avascular necrosis of the capital femoral epiphysis

Delayed proximal femoral epiphyseal ossification

Abnormality of the epiphyses of the feet

Abnormal upper limb epiphysis morphology

Broad femoral neck

Coxa vara

Short femoral neck

Delayed tarsal ossification

Metaphyseal irregularity

Short metacarpal

Abnormal hip joint morphology

Abnormal acetabulum morphology

Delayed ossification of carpal bones

Joint stiffness

Limited hip movement

Decreased hip abduction

Ankle pain

Knee pain

Epiphyseal dysplasia

Irregular epiphyses

Small epiphyses

Arthralgia of the hip

Hip dysplasia

Intervertebral disk degeneration

Multiple small vertebral fractures

Back pain

Premature osteoarthritis

Multiple epiphyseal dysplasia

Disease(s) Associated with MATN3

multiple epiphyseal dysplasia 5

Mouse Phenotypes

skeleton phenotype

increased chondrocyte apoptosis

decreased chondrocyte proliferation

osteoarthritis

short tibia

abnormal long bone morphology

abnormal long bone epiphyseal plate morphology

abnormal long bone epiphyseal plate proliferative zone

abnormal long bone hypertrophic chondrocyte zone

increased bone mass

abnormal chondrocyte morphology

Availability

Mouse Genotype

Matn3^tm1Asz/Matn3^tm1Asz

*

Matn3^tm1Brd/Matn3^tm1Brd

Matn3^tm1Mbri/Matn3^tm1Mbri

Matn3^tm1Mbri/Matn3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23