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Symbol
Name
ID
Orc1
origin recognition complex, subunit 1
MGI:1328337
Phenotype annotations related to cellular
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
cellular phenotype
polyploidy
increased hepatocyte karyomegaly
increased small intestinal crypt cell apoptosis
absent fibroblast proliferation
abnormal small intestinal crypt cell proliferation
increased hepatocyte proliferation
abnormal DNA replication
decreased DNA replication
increased DNA replication
Availability Mouse Genotype
Orc1tm1.1Gle/Orc1tm1.1Gle  (conditional)
Orc1tm1.1Gle/Orc1tm1.1Gle
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Orc1tm1.1Gle/Orc1tm1.1Gle
Tg(Cyp1a1-cre)1Dwi/0  (conditional)
Orc1tm1.1Gle/Orc1tm1.1Gle
Albtm1(cre/ERT2)Mtz/Alb+  (conditional)
*
Orc1tm1.1Gle/Orc1tm1.2Gle
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory