|
Symbol Name ID |
Men1
multiple endocrine neoplasia 1 MGI:1316736 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypercalcemia |
Hypophosphatemia |
Elevated circulating hepatic transaminase concentration |
Hypoglycemia |
Diabetes mellitus |
Dehydration |
Hyperphosphaturia |
Hypercalciuria |
Elevated circulating calcitonin concentration |
Elevated circulating parathyroid hormone level |
Hypergastrinemia |
Elevated circulating growth hormone concentration |
Increased circulating cortisol level |
Primary hypercortisolism |
Increased serum serotonin |
Chondrocalcinosis |
| Disease(s) Associated with MEN1 | ||||||||||||||||
| hyperparathyroidism | ||||||||||||||||
| multiple endocrine neoplasia type 1 | ||||||||||||||||
| pancreatic cancer |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal blood homeostasis |
decreased circulating glucose level |
hypoglycemia |
increased circulating corticosterone level |
increased circulating insulin level |
increased circulating calcium level |
decreased circulating phosphate level |
cyanosis |
|
| Availability | Mouse Genotype | |||||||||
| Men1tm1Ctre/Men1+ | ||||||||||
| Men1tm1Mmey/Men1+ | ||||||||||
| Men1tm1Rvt/Men1+ | * | |||||||||
| Men1tm1.2Ctre/Men1tm1.2Ctre Tg(PTH-cre)4167Slib/0 (conditional) |
||||||||||
| Men1tm1.2Ctre/Men1tm1.2Ctre Tg(Ins2-cre)1Heed/0 (conditional) |
||||||||||
| Men1tm1.2Ctre/Men1tm1.2Ctre Tg(Ins2-cre)1Dh/0 (conditional) |
||||||||||
| Men1tm1.2Ctre/Men1tm1.2Ctre Tg(Ins2-cre)25Mgn/0 (conditional) |
||||||||||
| Men1tm1.2Ctre/Men1tm1.2Ctre Pax3tm1(cre)Joe/Pax3+ (conditional) |
||||||||||
| Men1tm1.2Zqw/Men1tm1.2Zqw Tg(Ins2-cre)23Herr/0 (conditional) |
||||||||||
| Men1tm1Ctre/Men1tm1Ctre Tg(Pdx1-cre)89.1Dam/0 (conditional) |
||||||||||
| Men1tm1Ctre/Men1+ Tg(Pdx1-cre)89.1Dam/0 (conditional) |
||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|
|
||
Analysis Tools