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Symbol
Name
ID
Cldn4
claudin 4
MGI:1313314
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Elevated circulating hepatic transaminase concentration
Diabetes mellitus
Disease(s) Associated with CLDN4
pancreatic cancer

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased blood urea nitrogen level
increased circulating bicarbonate level
decreased fasting circulating glucose level
increased circulating aldosterone level
decreased circulating calcium level
increased circulating potassium level
increased circulating sodium level
increased circulating alanine transaminase level
abnormal renal calcium reabsorption
decreased circulating chloride level
increased urine chloride ion level
abnormal renal sodium reabsorption
increased urine sodium level
alkalosis
increased urine calcium level
Availability Mouse Genotype
Cldn4tm1.1Yham/Cldn4tm1.1Yham *
Cldn13em1(IMPC)J/Cldn13em1(IMPC)J
Cldn13tm1.1(KOMP)Vlcg/Cldn13tm1.1(KOMP)Vlcg
Cldn4tm1.1Jhou/Cldn4tm1.1Jhou
Tg(Aqp2-cre)1Dek/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory