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Symbol
Name
ID
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
MGI:1206581
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Webbed neck
Lower limb asymmetry
Hemihypertrophy
Splenomegaly
Overgrowth
Disease(s) Associated with PIK3CA
CLOVES syndrome

Mouse Phenotypes
embryonic growth retardation
decreased embryo size
increased pancreas weight
enlarged pancreas
decreased lean body mass
decreased body weight
increased body weight
kidney cyst
decreased body length
postnatal growth retardation
fetal growth retardation
visceromegaly
Availability Mouse Genotype
Pik3catm1Bvan/Pik3catm1Bvan
Pik3catm1Jdo/Pik3catm1Jdo
Pik3catm1Nbm/Pik3catm1Nbm
Pik3catm1Bvan/Pik3ca+
Pik3catm1.1Rzl/Pik3catm1.1Rzl
Tg(Fabp4-cre)1Blw/0  (conditional)
Gt(ROSA)26Sortm2(Pik3ca*)Dsa/Gt(ROSA)26Sor+
Ptf1atm1(cre)Hnak/Ptf1a+  (conditional)
Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky/Gt(ROSA)26Sor+
Tg(CAG-cre/Esr1*)5Amc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory