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Symbol
Name
ID

Myoc
myocilin
MGI:1202864

Phenotype annotations related to vision/eye

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes

Retinal arterial occlusion

Retinal vein occlusion

Abnormal anterior chamber morphology

Abnormality iris morphology

Abnormal optic nerve morphology

Increased cup-to-disc ratio

Temporal optic disc pallor

Optic neuropathy

Ocular hypertension

Myopia

High myopia

Visual impairment

Constriction of peripheral visual field

Peripheral visual field loss

Glaucomatous visual field defect

Central scotoma

Open angle glaucoma

Disease(s) Associated with MYOC

juvenile glaucoma

open-angle glaucoma

primary open angle glaucoma

Mouse Phenotypes		vision/eye phenotype	retina ganglion cell degeneration	optic nerve degeneration	abnormal canal of Schlemm morphology	abnormal trabecular meshwork morphology	abnormal retina neuronal layer morphology	abnormal retina inner plexiform layer morphology	abnormal intraocular pressure	ocular hypertension
Availability	Mouse Genotype	vision/eye phenotype	retina ganglion cell degeneration	optic nerve degeneration	abnormal canal of Schlemm morphology	abnormal trabecular meshwork morphology	abnormal retina neuronal layer morphology	abnormal retina inner plexiform layer morphology	abnormal intraocular pressure	ocular hypertension
	Myoc^tm2.1Rjo/Myoc^tm2.1Rjo	*!							!
	Tg(Myoc*Y423H)#Sit/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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