|
Symbol Name ID |
Smad3
SMAD family member 3 MGI:1201674 |
| Darker colors indicate more annotations |
| Human Phenotypes | Craniosynostosis |
Dolichocephaly |
Retrognathia |
Malar flattening |
Arachnodactyly |
Protrusio acetabuli |
Knee osteoarthritis |
Flexion contracture |
Camptodactyly |
Joint hypermobility |
Osteochondritis dissecans |
Abnormal sternum morphology |
Pectus carinatum |
Scoliosis |
Intervertebral disk degeneration |
Cervical spine instability |
Back pain |
Spondylolisthesis |
Osteoarthritis |
Hip osteoarthritis |
Neoplasm of the skeletal system |
| Disease(s) Associated with SMAD3 | |||||||||||||||||||||
| Loeys-Dietz syndrome 3 | |||||||||||||||||||||
| Lynch syndrome | |||||||||||||||||||||
| pancreatic cancer |
| Mouse Phenotypes | osteoarthritis |
abnormal carpal bone morphology |
abnormal tarsal bone morphology |
abnormal talus morphology |
increased width of hypertrophic chondrocyte zone |
abnormal sternum morphology |
abnormal thoracic cage morphology |
abnormal rib morphology |
kyphosis |
kyphoscoliosis |
decreased bone mineral density |
abnormal cartilage morphology |
abnormal chondrocyte morphology |
abnormal articular cartilage morphology |
abnormal joint morphology |
abnormal synovial joint capsule morphology |
calcified joint |
abnormal epiphyseal plate morphology |
abnormal skeleton physiology |
|
| Availability | Mouse Genotype | |||||||||||||||||||
| Smad3tm1Cxd/Smad3tm1Cxd | ||||||||||||||||||||
| Smad3tm1Xfw/Smad3tm1Xfw | ||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools