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Symbol Name ID |
Lmx1b
LIM homeobox transcription factor 1 beta MGI:1100513 |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormality of the eye |
Microcornea |
Keratoconus |
Microphakia |
Cataract |
Abnormal iris pigmentation |
Lester's sign |
Primary congenital glaucoma |
Ocular hypertension |
Glaucoma |
Open angle glaucoma |
Ptosis |
| Disease(s) Associated with LMX1B | ||||||||||||
| nail-patella syndrome |
| Mouse Phenotypes | corneal vascularization |
abnormal intraocular muscle morphology |
abnormal optic nerve morphology |
abnormal eye morphology |
abnormal anterior eye segment morphology |
abnormal iridocorneal angle |
absent trabecular meshwork |
abnormal ciliary body morphology |
absent ciliary body |
ciliary body hypoplasia |
abnormal iris morphology |
abnormal iris stroma morphology |
iris stroma hypoplasia |
irregularly shaped pupil |
iris hypoplasia |
anterior iris synechia |
abnormal cornea morphology |
abnormal Descemet membrane morphology |
abnormal corneal endothelium morphology |
decreased corneal epithelium thickness |
abnormal corneal stroma morphology |
cornea ulcer |
corneal opacity |
corneal scarring |
decreased eye anterior chamber depth |
abnormal lens morphology |
abnormal lens epithelium morphology |
small lens |
macrophthalmia |
buphthalmos |
microphthalmia |
ocular hypertension |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||
| Lmx1btm1Rjo/Lmx1btm1Rjo | |||||||||||||||||||||||||||||||||
| Lmx1bIcst/Lmx1b+ | |||||||||||||||||||||||||||||||||
| Lmx1btm1Rjo/Lmx1btm4.1Rjo H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Lmx1btm1Rjo/Lmx1btm4.1Rjo Pitx2tm4(cre)Jfm/Pitx2+ (conditional) |
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| Lmx1btm1Rjo/Lmx1btm4.1Rjo Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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